A new study in JAMA showed that a blood test was able to accurately predict Alzheimer's disease with 88%-92% accuracy. The current best methods to diagnose Alzheimer's disease include spinal fluid samples and PET scans. Interestingly, dementia specialists have a 73% accuaracy of diagnosing Alzheimer's disease and primary care physicians have only a 61% accuracy rate. The test has not yet been approved by the FDA or health plans since more studies need to be done to confirm the results of the new study.
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New Immunotherapy treatments for Alzheimer's disease approved by the FDA
Most of the FDA approved treatments for Alzheimer's Disease address symptoms but not progression of the disease. Recently the FDA has approved 2 new drugs that can treat the actual cognitive impairment of Alzheimer's Disease that work by removing abnormal beta-amyloid from the brain. The problem is that the side effect profile of the new drugs include cerebral edema and hemorrhage. Additionally, both medications are given as IV infusions. Lecanemab is given through IV over one hour every two weeks and Donanemab is given through IV over approximately 30 minutes every four weeks.
https://www.nia.nih.gov/health/alzheimers-treatment/how-alzheimers-disease-treated#future
